Cerebral Paragonimiasis Treated with Praziquantel: Case Report.
- Author:
Chang Hun RHEE
1
;
Hee Won JUNG
;
Seung Yull CHO
;
Hyo Chung SOHN
Author Information
1. Department of Neurosurgery, Seoul National University, Korea.
- Publication Type:Original Article
- Keywords:
Cerebral paragonimiasis;
Praziquantel;
Brain CT;
Micro-ELISA
- MeSH:
Adult;
Brain;
Diagnosis;
Female;
Follow-Up Studies;
Headache;
Humans;
Immunoglobulin G;
Intradermal Tests;
Korea;
Paragonimiasis*;
Paragonimus westermani;
Parasitic Diseases;
Praziquantel*;
Vomiting
- From:Journal of Korean Neurosurgical Society
1987;16(3):853-858
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cerebral paragonimiasis, occuring as an extrapulmonary infestation, still reamans an important intracranial parasitic disease in Korea. The authors report a 32-year-old female patient who had developed headache, vomiting and signs of the left hemispheric dysfunction for 5 months. A diagnosis of the cerebral paragonimiasis was made on the basis of brain CT findings, a positive intradermal test, and the positive results of serum and CSF levels of the anti-Paragonimus IgG antibodies(by micro-ELISA). She was treated with 75 mg/kg/day of praziquantel for 7days to confirm healing of the intracranial lesion by the follow-up brain CT and micro-ELISA associated with a marked clinical improvement. This case report highly suggests the anticipated effectiveness of praziquantel in the treatment of the cerebral infestation of Paragonimus westermani, especially in its early stage.
