A Case of Pyoderma Gangrenosum Associated with Autoimmune Chronic Active Hepatitis.
- Author:
Seok Beom HONG
1
;
Ik Joon KANG
;
Jung IL LEE
;
Nack In KIM
Author Information
1. Department of Dermatology, College of Medicine, Kyung Hee University, Seoul, Korea. nikim@khmc.or.kr
- Publication Type:Case Report
- Keywords:
Pyoderma gangrenosum;
Autoimmune hepatitis
- MeSH:
Adult;
Antibodies, Antinuclear;
Arthritis, Rheumatoid;
Female;
Hepatitis, Autoimmune;
Hepatitis, Chronic*;
Humans;
Inflammatory Bowel Diseases;
Liver;
Pyoderma Gangrenosum*;
Pyoderma*;
Ulcer
- From:Korean Journal of Dermatology
2004;42(4):460-463
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pyoderma gangrenosum (PG) is an inflammatory ulcerative condition of unclear etiology. In more than 50% of cases, lesions occur in association with an underlying systemic disorder-most notably; inflammatory bowel disease (IBD), rheumatoid arthritis, or a hematologic abnormality. Here, we report a rare case of pyoderma gangrenosum associated with autoimmune chronic active hepatitis. A 34-year-old woman presented with a 2-month history of a painful ulceration on her back. She was clinically diagnosed as having pyoderma gangrenosum and an appropriate exclusion was performed. She had abnormal results for liver biochemical tests, with a hepatitis-like picture and high titer of antinuclear antibodies. According to the scoring system proposed by the International Autoimmune Hepatitis Group she had `definite' autoimmune hepatitis and responded well to immunesuppressive treatment.