A Case of Allergic Contact Dermatitis Due to Topical Minoxidil.
- Author:
Kweon Soo KANG
1
;
Bo Hyun LEE
;
Hee Jin HAN
;
Chun Wook PARK
;
Cheol Heon LEE
Author Information
1. Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea. knderma@netian.com
- Publication Type:Case Report
- Keywords:
Allergic contact dermatitis;
Minoxidil
- MeSH:
Adult;
Alopecia;
Dermatitis, Allergic Contact*;
Hair;
Humans;
Male;
Minoxidil*;
Patch Tests;
Propylene Glycol;
Scalp
- From:Korean Journal of Dermatology
2004;42(4):500-502
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Minoxidil (2, 6-diamino-4-piperidinopyrimidine 1-oxide) is a systemic antihypertensive agent, the topical application of which has been shown to produce hair growth. Topical minoxidil solution (5% minoxidil, propylene glycol, alcohol, water) has generally been well-tolerated, but allergic contact dermatitis has been reported. When allergic contact dermatitis to minoxidil solution is suspected, evaluation of ingredients of minoxidil solution should be performed because allergic contact dermatitis due to propylene glycol in minoxidil solution has been frequently reported. A 34-year-old male presents with a diffuse erythematous patch on the scalp. He has applied minoxidil solution for 7 days due to androgenic alopecia. A Patch test with Korean standard series and the ingredients of used topical agents showed positive reactions to 1%, 2% and 5% minoxidil solution.