A Case of Anticonvulsant Hypersensitivity Syndrome Induced by Carbamazepine.
- Author:
Seok Yeol PARK
1
;
Joo Yong KIM
;
Chang Wook KIM
;
Byung Chun KIM
;
Kyu Suk LEE
Author Information
1. Department of Dermatology, Keimyung University School of Medicine Taegu, Korea. sfpsy@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Anticonvulsant Hypersensitivity syndrome;
Carbamazepine
- MeSH:
Abnormalities, Multiple;
Aged;
Anticonvulsants;
Carbamazepine*;
Eosinophilia;
Exanthema;
Fever;
Humans;
Hypersensitivity*;
Leukocytosis;
Lymphatic Diseases;
Male;
Phenobarbital;
Phenytoin;
Skin
- From:Korean Journal of Dermatology
2004;42(4):523-526
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anticonvulsant hypersensitivity syndrome is a life threatening immunologic reaction of anticonvulsants therapy such as phenytoin, phenobarbital, or carbamazepine, characterized by multiple abnormalities such as fever, rash, lymphadenopathy, acute hepatocellular injury, leukocytosis, and eosinophilia. We report a case of anticonvulsant hypersensitivity syndrome thought to be caused by the use of carbamazepine in a 65-year-old male. He developed erythematous skin eruption four weeks after beginning therapy with carbamazepine. The clinical, laboratory and histologic findings of this patient were compatible with anticonvulsant hypersensitivity syndrome.
