Clinical feature and treatment of bisphosphonate-related osteonecrosis of jaw about oral bisphosphonate administrated patients: case reports.
10.5125/jkaoms.2010.36.6.508
- Author:
Woo Sung CHOI
1
;
Hyun Joong YOON
;
Sang Hwa LEE
Author Information
1. Department of Oral and Maxillofacial Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. justina@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Bisphosphonate;
Osteonecrosis;
Osteoporosis
- MeSH:
Administration, Oral;
Clinical Protocols;
Diphosphonates;
Humans;
Jaw;
Multiple Myeloma;
Osteonecrosis;
Osteoporosis;
Surgery, Oral;
Treatment Outcome
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2010;36(6):508-514
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bisphosphonates are used effectively for many medical conditions, such as multiple myeloma, Paget's disease, osteoporosis, etc. However, recently, osteonecrosis of the jaw was observed in patients receiving long-term bisphosphonate therapy, including oral administration. This osteonecrosis is refractory, and complete recovery is not guaranteed despite a standard treatment protocol being established by many associations related to oral and maxillofacial surgery. The treatment outcome of oral bisphosphonate-related osteonecrosis of jaw (BRONJ) is reported with a review of the relevant literature.
