Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR-Mutant Lung Cancer.
10.4046/trd.2014.77.6.271
- Author:
Mihong CHOI
1
;
Youngjoo LEE
;
Sang Hyun HWANG
;
Jin Soo LEE
Author Information
1. Department of Internal Medicine, Center for Diagnostic Oncology, National Cancer Center, Goyang, Korea. yjlee@ncc.re.kr
- Publication Type:Case Report
- Keywords:
EGFR Tyrosine Kinase Inhibitor 324674;
Nocardia Infections;
Carcinoma, Non-Small-Cell Lung;
Radiosurgery
- MeSH:
Carcinoma, Non-Small-Cell Lung;
Humans;
Lung Neoplasms*;
Nocardia Infections*;
Protein-Tyrosine Kinases;
Radiosurgery;
Receptor, Epidermal Growth Factor
- From:Tuberculosis and Respiratory Diseases
2014;77(6):271-273
- CountryRepublic of Korea
- Language:English
-
Abstract:
Disease flare-up after discontinuing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been considered as a critical issue in lung cancer patients who have experienced radiologic progression after showing initial durable response. This is a case of systemic nocardiosis that occurred after chronic steroid use for radionecrosis from stereotactic radiosurgery. It was initially thought as a disease flare-up after stopping EGFR-TKI.
