A Case of Antiphospholipid Syndrome Refractory to Secondary Anticoagulating Prophylaxis after Deep Vein Thrombosis-Pulmonary Embolism.
10.4046/trd.2014.77.6.274
- Author:
Kang Mo GU
1
;
Jong Wook SHIN
;
In Won PARK
Author Information
1. Division of Allergy and Pulmonary Medicine, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea. iwpark@cau.ac.kr
- Publication Type:Case Report
- Keywords:
Antiphospholipid Syndrome;
Venous Thrombosis;
Pulmonary Embolism;
Cerebrovascular Disorders;
Blue Toe Syndrome
- MeSH:
Adolescent;
Antibodies, Antiphospholipid;
Antiphospholipid Syndrome*;
Blue Toe Syndrome;
Cerebral Infarction;
Cerebrovascular Disorders;
Embolism*;
Humans;
Male;
Mortality;
Pregnancy;
Pulmonary Embolism;
Recurrence;
Thromboembolism;
Thrombosis;
Veins*;
Venous Thrombosis
- From:Tuberculosis and Respiratory Diseases
2014;77(6):274-278
- CountryRepublic of Korea
- Language:English
-
Abstract:
Antiphospholipid syndrome (APS) is an acquired systemic autoimmune disorder characterized by a combination of clinical criteria, including vascular thrombosis or pregnancy morbidity and elevated antiphospholipid antibody titers. It is one of the causes of deep vein thrombosis and pulmonary embolism that can be critical due to the mortality risk. Overall recurrence of thromboembolism is very low with adequate anticoagulation prophylaxis. The most effective treatment to prevent recurrent thrombosis is long-term anticoagulation. We report on a 17-year-old male with APS, who manifested blue toe syndrome, deep vein thrombosis, pulmonary thromboembolism, and cerebral infarction despite adequate long-term anticoagulation therapy.
