The effect of carbon dioxide pneumoperitoneum on baroreflex sensitivity.
10.4097/kjae.2008.55.6.662
- Author:
Seunghyun CHUNG
1
;
Hun CHO
;
Kyoung Ok KIM
;
Younsuk LEE
;
Jun Gwon CHOI
;
Junyong IN
;
Yun Suk CHOE
Author Information
1. Department of Anesthesiology and Pain Medicine, Dongguk University Ilsan Hospital, Goyang, Korea. cho126@duih.org
- Publication Type:Original Article
- Keywords:
autonomic nervous system;
baroreflex sensitivity;
carbon dioxide;
laparoscopy;
pneumoperitoneum
- MeSH:
Adult;
Anesthesia, General;
Autonomic Nervous System;
Baroreflex;
Blood Pressure;
Carbon;
Carbon Dioxide;
Electrocardiography;
Female;
Gynecologic Surgical Procedures;
Heart Rate;
Hemodynamics;
Humans;
Laparoscopy;
Methyl Ethers;
Pneumoperitoneum
- From:Korean Journal of Anesthesiology
2008;55(6):662-665
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: To determine if positive pressure pneumoperitoneum has adverse effects on autonomic nervous system function, we examined baroreflex sensitivity (BRS) during carbon dioxide pneumoperitoneum in patients undergoing laparoscopic surgery. METHODS: Twenty adult patients scheduled for laparoscopic gynecologic surgery were selected for the study. After general anesthesia was induced with sevoflurane, continuous electrocardiography and blood pressure were monitored. Spontaneous BRS was achieved using sequence method immediately before, and 5 minutes after, pneumoperitoneum. Heart rate variability (HRV) was also determined. RESULTS: After pneumoperitoneum, BRS decreased from 12.9 +/- 1.8 ms/mmHg to 8.1 +/- 1.1 ms/mmHg (P < 0.05), and the power of the high frequency band decreased from 237.8 ms2/Hz to 49.6 ms2/Hz (P < 0.05). CONCLUSIONS: Compared to recordings obtained before pneumoperitoneum, BRS was decreased during pneumoperitoneum. This may predispose patients undergoing laparoscopic surgery to hemodynamic instability in addition to pneumoperitoneum itself.
