Association between Metabolic Syndrome and Gallbladder Polyps in Healthy Korean Adults.
10.3346/jkms.2013.28.6.876
- Author:
Eun Jung PARK
1
;
Hong Soo LEE
;
Sang Hwa LEE
;
Hye Jin CHUN
;
Sun Young KIM
;
Yu Kyung CHOI
;
Hee Jeong RYU
;
Kyung Won SHIM
Author Information
1. Department of Family Medicine, Ewha Womans University College of Medicine, Mokdong Hospital, Seoul, Korea. ewhashim@ewha.ac.kr
- Publication Type:Original Article
- Keywords:
Metabolic Syndrome;
GB Polyp;
Risk Factors
- MeSH:
Adult;
Age Factors;
Asian Continental Ancestry Group;
Female;
Gallbladder Diseases/*diagnosis/etiology;
Hepatitis B Surface Antigens/blood;
Humans;
Logistic Models;
Male;
Metabolic Syndrome X/complications/*diagnosis;
Middle Aged;
Odds Ratio;
Republic of Korea;
Risk Factors;
Severity of Illness Index;
Sex Factors
- From:Journal of Korean Medical Science
2013;28(6):876-880
- CountryRepublic of Korea
- Language:English
-
Abstract:
The goal of this study was to evaluate the association between gallbladder (GB) polyps and metabolic syndrome. A total of 5,685 healthy subjects were included, and 485 of these subjects had GB polyps and 744 had metabolic syndrome. In this study, metabolic syndrome was diagnosed according to standards suggested by the AHA/NHLBI ATP III 2005, and abdominal obesity (> or = 90 cm in men and > or = 85 cm in women for Korean) was diagnosed according to standards set forth by the Korean Society for Study of Obesity. Biphasic logistic regression adjusted for age and gender was used to evaluate the association between metabolic syndrome and GB polyps. Subjects who were male (OR, 1.493; 95% CI, 1.11-2.00) and hepatitis B suface Ag (HBsAg) positive (OR, 1.591; 95% CI, 1.06-2.38) were significantly more likely to have GB polyps. The metabolic syndrome group had a higher risk of GB polyps (OR, 1.315; 95% CI, 1.01-1.69) than the group without metabolic syndrome. In conclusion, subjects who were HBsAg positive and male appear to be associated with the risk of GB polyps. The presence of metabolic syndrome also appears to be associated with the risk of GB polyps in Koreans.
