Malignant Sertoli cell tumor in Shih Tzu dog.
- Author:
Sang Chul KANG
1
;
Hyoung Seok YANG
;
Ji Youl JUNG
;
Eun Hye JUNG
;
Hee Chun LEE
;
Eui Kyung HWANG
;
Jae Hoon KIM
Author Information
1. College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690-756, Korea. kimjhoon@jejunu.ac.kr
- Publication Type:Case Report
- Keywords:
cryptorchid testis;
dog;
immunohistochemistry;
malignant Sertoli cell tumor
- MeSH:
Abdomen;
Alopecia;
Anemia;
Animals;
Anorexia;
Constipation;
Dogs;
Epistaxis;
European Continental Ancestry Group;
Humans;
Immunohistochemistry;
Keratins;
Lymph Nodes;
Male;
Neoplasm Metastasis;
Phosphopyruvate Hydratase;
Preschool Child;
Sertoli Cell Tumor;
Testis;
Urinary Incontinence;
Vimentin
- From:Korean Journal of Veterinary Research
2011;51(2):171-175
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.
