A Case of Nodular Amyloidosis.
10.5021/ad.1999.11.1.47
- Author:
Seok Ki JUNG
;
Seung Ho CHANG
;
Tae Young YOON
- Publication Type:Case Report
- Keywords:
Nodular amyloidosis
- MeSH:
Adult;
Amyloidosis*;
Birefringence;
Congo Red;
Dermis;
Eosine Yellowish-(YS);
Hematoxylin;
Humans;
Male;
Microscopy;
Scalp;
Skin
- From:Annals of Dermatology
1999;11(1):47-50
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 38-year-old male patient visited our clinic complaining of three skin lesions on the scalp. There were yellowish to brownish, waxy, non-tender, walnut-sized nodules. Hematoxylin and eosin staining revealed amorphous pinkish material deposits in the dermis. The Congo red stain and Dylon stain under polarizing microscopy showed yellow-green birefringence and the immunoglobulin-lambda light chain stain showed a positive reaction. An electron microscopic examination revealed filaments with uniform diameter(6 to 10nm) that were straight and neither branched nor anastomosed. Based on the clinical, histopathological, immunohistochemical and electron microscopical findings, the skin lesions were diagnosed as nodular amyloidosis.