Aggravation of Hypertriglyceridemia and Acute Pancreatitis in a Bipolar Patient Treated with Quetiapine.
10.3349/ymj.2014.55.3.831
- Author:
Li Syue LIOU
1
;
Yi Jen HUNG
;
Chang Hsun HSIEH
;
Fone Ching HSIAO
Author Information
1. Department of Family and Community Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
- Publication Type:Case Report ; Review
- Keywords:
Quetiapine;
hypertriglyceridemia;
pancreatitis
- MeSH:
Acute Disease;
Bipolar Disorder/*drug therapy/*psychology;
Dibenzothiazepines/*therapeutic use;
Humans;
Hypertriglyceridemia/*drug therapy/*psychology;
Pancreatitis/*drug therapy/*psychology
- From:Yonsei Medical Journal
2014;55(3):831-833
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pancreatitis is a very rare adverse effect of quetiapine treatment, with only 5 cases of quetiapine-associated pancreatitis reported in the English literature to date. Herein, we report one patient who developed severe hypertriglyceridemia (>1000 mg/dL) after quetiapine administration, resulting in acute pancreatitis. An analysis of the underlying pathogenic mechanisms and a review of relevant literature are also presented. Clinicians should be aware of the potentially life-threatening metabolic disturbances and/or pancreatitis associated with quetiapine therapy.
