Antigenic relationship between mugwort and ragweed pollens by crossed immunoelectrophoresis.
10.3346/jkms.1994.9.3.213
- Author:
Hae Sim PARK
1
;
Mi Jung KIM
;
Hee Bom MOON
Author Information
1. Department of Internal Medicine National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
ragweed;
mugwort;
pollen;
antigen
- MeSH:
Animal;
Antibodies/immunology;
Cross Reactions;
Immunoelectrophoresis, Two-Dimensional;
Pollen/*immunology;
Rabbits
- From:Journal of Korean Medical Science
1994;9(3):213-217
- CountryRepublic of Korea
- Language:English
-
Abstract:
Mugwort and ragweed pollens have been considered as important respiratory allergens in Korea. These two pollens are abundant in the air of Seoul from August through October. Many ragweed-sensitive patients have shown concurrent sensitivities to mugwort pollen. However the antigenic relationship between these two pollens has not been clarified. To observe the cross-reactivity between them, we developed polyclonal anti-mugwort and anti-ragweed antibodies by immunization on New Zealand white rabbits, and performed crossed immunoelectrophoresis(CIE) with two pollen extracts. Five precipitation lines were formed by mugwort and anti-mugwort antibody. One precipitation line was formed by ragweed and anti-ragweed antibody. There was no reaction from mugwort and anti-ragweed antibody, and from ragweed and anti-mugwort antibody. These results indicate that there is no cross-antigenicity between mugwort and ragweed pollens.
