A Case of Idiopathic CD4 + T Lymphocytopenia Associated with Kaposi's Sarcoma.
- Author:
Hyun Tae LEE
;
Ho Sun JANG
;
Kyung Sool KWON
;
Tae Ahn CHUNG
- Publication Type:Case Report
- Keywords:
Idiopathic CD4+ T lymphocytopenia;
Kaposis sarcoma
- MeSH:
Adult;
Centers for Disease Control and Prevention (U.S.);
Diagnosis;
Extremities;
Female;
HIV Infections;
HIV-1;
Humans;
Lung;
Lymphopenia*;
Pneumonia, Pneumocystis;
Sarcoma, Kaposi*;
Scalp;
Serologic Tests;
T-Lymphocyte Subsets;
T-Lymphocytes;
T-Lymphocytes, Helper-Inducer;
T-Lymphocytopenia, Idiopathic CD4-Positive;
Thorax;
Toes
- From:Korean Journal of Dermatology
1997;35(1):191-195
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Idiopathic CD4+ T lymphocytopenia (ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection. We report a case of ICL associated with Kaposis sarcoma (KS) and pneumocystis carinii pneumonia (PCP) in a 34-year old woman. She developed violaceous, protruding masses on scalp, back, both extremities, palms, soles, left. first toe and peritonsillar region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1, 2 and HTLV I, -II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involuement of KS, she died at 22nd day after admission.
