Evaluation of specific IgE antibody in Clonorchis sinensis infection.

Author: Duk Young MIN ¹ ; Chin Thack SOH
Author Information

1. Department of Parasitology, Yonsei University Medical College, Institute of Tropical Medicine, Yonsei University, Korea.
Publication Type:Original Article
MeSH: parasitology-helminth-trematoda; Clonorchis sinensis; clonorchiasis; immunology; radioimmunosorbent test; radioallergosorbent test; IgA; IgE; serum
From:The Korean Journal of Parasitology 1983;21(1):27-31
CountryRepublic of Korea
Language:English
Abstract: Serum IgE level and Clonorchis specific IgE in individuals with Clonorchis sinensis were determined by radioimmunosorbent(RIST) and radioallergosorbent technique(RAST) respectively. Highly significant elevations of serum IgE (P<0.001) and specific IgE antibodies (P<0.01) were observed in area from individuals with clonorchiasis. The mean values of serum IgE in individuals with clonorchiasis and healthy individuals were 2,372 IU/ml and 364 IU/ml respectively and specific IgE antibodies of both groups were 52.0 and 4.4%. A close correlation(r=0.9451) between serum IgE level and specific IgE antibodies were observed and correlation (r=0.6056) between serum IgE and EPG and between specific IgE and EPG(r=0.5693) were also observed.