The Change of Soluble Intercellular Adhesion Molecule-1 Levels in Hemorrhagic Fever with Renal Syndrome.
- Author:
Ho Cheol SONG
;
Chul Hee PARK
;
Chul Woo YANG
;
Jung Hee PARK
;
Young Ok KIM
;
Suk Young KIM
;
Euy Jin CHOI
;
Yoon Sik CHANG
;
Byung Kee BANG
;
Yoo Hyun PARK
;
Byung Su KIM
- Publication Type:Original Article
- Keywords:
Hemorrhagic fever with renal syndrome;
Intercellular adhesion molecule-1
- MeSH:
Convalescence;
Hemorrhagic Fever with Renal Syndrome*;
Humans;
Intercellular Adhesion Molecule-1*;
Platelet Count
- From:Korean Journal of Nephrology
1998;17(5):708-713
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The serum levels of sICAM-1 were significantly higher in febrile & hypotensive (789+/-241ng/ml) stage than in diuretic stage (514+/-151ng/ml) and convalescence stage (410+/-88ng/ml) (P<0.01). Also the serum levels of sICAM-1 in oliguric (628+/-220ng/ml) stage higher than that of convalescence stage (P<0.01). The serum level of sICAM-1 was significantly high in convalescence stage of patients with HFRS compared to control (306+/-75ng/ml) (P<0.01). sICAM-1 levels correlated with platelet count (R=-0.35, P<0.05) in all stage of HFRS. Our results suggest that the enhanced immune activation is a common feature in early stage of HFRS.
