A Case of Gougerot-Blum Syndrome with Leukemia.
- Author:
Ki Bum MYUNG
;
Hong Jin KIM
;
Sung Nack LEE
- Publication Type:Original Article
- MeSH:
6-Mercaptopurine;
Adult;
Arm;
Bone Marrow;
Cyclophosphamide;
Epistaxis;
Exanthema;
Female;
Gingiva;
Granulocyte Precursor Cells;
Hemorrhage;
Humans;
Leg;
Leukemia*;
Leukemia, Myeloid, Acute;
Prednisolone;
Rare Diseases;
Skin
- From:Korean Journal of Dermatology
1977;15(4):499-503
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gougerost-Blum syndrome is a rare disease and characterized by lichenoid papules in association with purpuric lesions. So far as we know there has been no report of, in literatures, Gougerot-Blum syndrome with leukemia. We experienced a case of typical Gougerrot_Blum syndrome with acute myeloblastic leukemia in a 30 year-old female patient. This patient complained of rashes on whole body for 2 months, and frequent epistaxis and gum bleeding for 20 days. The skin revealed miliary to rice sized rusty colored lichenoid papules on whole body especially on legs and arms. Histopathologically the skin showed the picture of Gougerot-Blum syndrome. On peripheral blood examination and bone marrow aspiration myeloblastic leukemia was confirmed. The patient was treated with 6-mercaptopurine, cytoxan and prednisolone with slight improvement of skin lesions, but no improvement of leukumia itselt.
