A Case of Acute Generalized Exanthematous Pustulosis with Erythema Multiforme-like lesions.
- Author:
Jin Seok YANG
1
;
Jung Hoon LEE
;
Ji Youn SONG
;
Tae Yoon KIM
;
Jun Young LEE
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. UBJDER@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Acute generalized exanthematous pustulosis;
Erythema multiforme-like features
- MeSH:
Acute Generalized Exanthematous Pustulosis*;
Blister;
Edema;
Erythema*;
Female;
Fever;
Histamine Antagonists;
Humans;
Middle Aged;
Neutrophils;
Purpura;
Recurrence
- From:Korean Journal of Dermatology
2003;41(5):630-633
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute generalized exanthematous pustulosis(AGEP) is a disease entity caused mostly by drugs or viral infections. Clinically, it manifests as generalized erythema and tiny pustules with fever, but may manifest targetoid lesions, purpura, edema, blisters and mucosal erosions in addition to pustules. We describe a case of AGEP with erythema multiforme-like features in a 46 year old woman who presented with acute onset of high fever and a noticeably polymorphic eruption consisting of numerous tiny pustules on erythematous bases, edematous targetoid lesions and purpuric lesions. The histology revealed subcorneal neutrophilic pustules on the tiny pustular lesions and markedly papillary dermal edema on the erythema multiforme-like lesions. Systemic corticosteroid and antihistamines were initiated, resulting in rapid resolution without recurrence.