Two Cases of Alopecia Totalis treated with Diphenylcyclopropenone (DPCP) Immunotherapy.
10.12701/yujm.2006.23.2.232
- Author:
Seok Ki MOON
1
;
Young Min SHIN
;
Chan Woo KIM
;
Dong Hoon SHIN
;
Jong Soo CHOI
;
Ki Hong KIM
Author Information
1. Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. khkim@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Diphenylcyclopropenone (DPCP);
Alopecia totalis;
Alopecia areata
- MeSH:
Alopecia Areata;
Alopecia*;
Dinitrochlorobenzene;
Hair;
Immunotherapy*;
Injections, Intralesional;
Scalp
- From:Yeungnam University Journal of Medicine
2006;23(2):232-239
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Treatments for alopecia areata include topical corticosteroid treatment, corticosteroid intralesional injection, systemic corticosteroid treatment, PUVA(psoralen-UVA) and topical immunotherapy. The therapeutic effects are variable. Alopecia totalis is hard to treat completely. Topical immunotherapy with dinitrochlorobenzene (DNCB), squaric acid dibutyl ester (SADBE) or diphenylcyclopropenone (diphencyprone, DPCP) represents the most accepted therapeutic modality for the treatment of extensive alopecia areata. We report two cases of alopecia totalis treated with DPCP. After DPCP treatment, total scalp hair was completely recovered.