Systemic Lupus Erythematosus With Involvement Of Liver And Central Nervous System: A Case Report.
- Author:
Sang Cheol LEE
1
;
Soo Kon LEE
;
Chein Soo HONG
;
Chan Il PARK
Author Information
1. Department of Internal Medicine, College of Wonju Medicine, Yonsei University, Wonju, Korea.
- Publication Type:Case Report
- Keywords:
systemic lupus erythematosus;
lupoid hepatitis;
CNS-SLE;
SPECT
- MeSH:
Brain;
Cause of Death;
Central Nervous System*;
Hepatitis, Autoimmune;
Humans;
Liver Diseases;
Liver*;
Lupus Erythematosus, Systemic*;
Magnetic Resonance Imaging;
Tomography, Emission-Computed, Single-Photon
- From:The Journal of the Korean Rheumatism Association
1994;1(1):91-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a pateint with CNS-SLE who initially manifested liver involvement. We emphasize the difficulty in differentiating autoimmune hepatitis and hepatic involvement of SLE, clinically, immunologically, radiologically, pathologically. Neuropsychiatric disorders casued by lupus activity occur during the course of the illness in 35~75% of patients with SLE. It is a poor prognostic sign and frequent cause of death in lupus patients. Recently some evidence suggest that single-photon-emission computed tomography(SPECT) of brain is useful for detecting abnormalities of regional cerebral blood flow in patients with CNS lupus. We were able to conclude that CNS symptoms in this patient were due to CNS involovement of SLE. Although MRI of brain showed some high signal intensity in parenchyme of brain, this findings were said to be common in chronic liver diseases. In this situdation we think that SPECT of brain might be performed for differentiation of the cause of CNS symptoms in SLE patient with chronic liver disease.
