A Case Of Rheumatoid Arthritis Accompanied By Severe Eosinophilia.
- Author:
Chong Il SOHN
1
;
Myeong Kon KIM
;
Kee Chang LEE
;
Sung Soo JUNG
;
In Hong LEE
;
Sang Cheol BAE
;
Dae Hyun YOO
;
Seong Yoon KIM
;
Wha Soon CHUNG
Author Information
1. Rheumatism Center, Department of Internal Medicine College of Medicine, Hanyang University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Rheumatoid arthritis;
eosinophilia
- MeSH:
Arthritis, Rheumatoid*;
Collagen Diseases;
Eosinophilia*;
Eosinophils;
Female;
Humans;
Hypereosinophilic Syndrome;
Middle Aged;
Outpatients;
Parasites;
Polyarteritis Nodosa;
Rheumatic Diseases;
Sarcoidosis
- From:The Journal of the Korean Rheumatism Association
1994;1(1):98-102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Eosinophilia is usually accompanied by parasite infestation, allergic condition, drug, collagen disease, and idiopathic hypereosinophilic syndrome. In about 10 to 40% of rheumatoid arthritis patients, peripheral blood reveals eosinophilia. Of the rheumatic disease, eosinophilia may occur in rheumatoid arthritis, sarcoidosis, polyarteritis nodosa and other vascultis. Patient with eosinophilia must be carefully followed up due to possibility of progression to eosinophilic leukemia or myeloproliferatire disease. We experienced a case of rheumatoid arthritis with severe eosinophilia for a period of more than one year in a 53 year-old female patient, eosinophil more than 85% in the peripheral blood, but in spite of careful laboratory study, there was no evidence of parasite infestation, allergic disease and malignant condition that may cause eosinophilia. Therefore we concluded that her severe eosinophilia was associated with rheumatoid arthritis itself, and now she is intensively followed up at the outpatient department. We have to look for any malignant transformation during her clinical course. Marked eosinophilia associated with rheumatoid arthritis is very rare, so we report this case with a review of literatures.
