A Case of Lymphocytic Infundibuloneurohypohysitis.
- Author:
Hee Bok CHAE
1
;
Joong Yeol PARK
;
Young Ki SHONG
;
Kyung Jo KIM
;
Chul Hee KIM
;
Byoung Duk KWUN
;
Ghee Young CHOE
;
Jin Bok HWANG
;
Ghi Su KIM
Author Information
1. Department of Medicine, Asan Medical Center, Collee of Medicine, University of Ulsan, Seoul, Korea.
- Publication Type:Case Report
- MeSH:
Brain;
Craniotomy;
Diabetes Insipidus, Neurogenic;
Follow-Up Studies;
Headache;
Humans;
Magnetic Resonance Imaging;
Male;
Pituitary Gland;
Pituitary Gland, Posterior;
Pituitary Neoplasms;
Polyuria;
Water Deprivation
- From:Korean Journal of Medicine
1997;52(3):424-428
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lymphocytic infundibuloneurohypphysitis(LINH) is a newly classified disorder and proposed as a common cause of idiopathic central diabetes insipidus. It is characterized by thickening of the infundibulum and/or pituitary stalk and absence of high signal in the neurohypophysis in sellar MRI and the microscopic findings of diffuse lymphocytic infiltration within the neurohypophysis. A 12year-old boy presented polyuria and headache. The result of water deprivation test was compatible with central diabetes insipidus. Brain MRI showed thickening of the pituitary stalk and loss of high signal in the neurohypophysis. Craniotomy and excisional bi6opsy was done under the impression of pituitary tumor. Microscopically, neurohypophysis showed dense lymphocytic infiltration and no malignant cells. Six months after the operation, the previously thickened pituitary stalk and neurohypophysis appeared normal in follow-up MRI.
