Wilson`s Disease with Abnormal Secretion of Pituitary Hormones.
- Author:
Dae Hyun KIM
1
;
Bum Chan KWEON
;
Han Keun LEE
;
Keun Ha NAM
;
Seog Jun KIM
;
Dong Wook LEE
;
Chan Gyu PARK
;
Chang Gi LEE
;
Sang Moon LEE
;
Choong Ki LEE
Author Information
1. Department of Internal Medicine, Fatima Hospital, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Wilson`s disease;
pituitary hormones;
Penicillamine hypersensitivity
- MeSH:
Adolescent;
Anemia, Hemolytic;
Brain;
Copper;
Fibrosis;
Hepatitis, Chronic;
Hepatolenticular Degeneration;
Humans;
Hypersensitivity;
Korea;
Liver;
Penicillamine;
Pituitary Hormones*;
Puberty, Delayed
- From:Korean Journal of Medicine
1997;52(3):429-435
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Wilson`s disease is a hereditary disorder in hepatic excretion of copper that results in toxic accumulations of the metal in liver, brain and other organs. Though there have been some reports of Wilson's disease with hepatic, neurologic, psychiatric symptoms, or hemolytic anemia, a case of Wilson's disease with abnormal secretion of pituitary hormones is, to our best knowledge, the first report in Korea. We report a case of Wilson`s disease with abnormal secretion of pituirary hormones, chronic active hepatitis with feature of early cirrhosis and hemolytic anemia in 18-year-old man showing delayed puberty. And also we describe a case of successful desensitization to penicillamine in a penicillamine hypersensitivity.
