Bilateral Frontal Polymicrogyria: An Autopsy Case Report.
10.4132/KoreanJPathol.2011.45.S1.S62
- Author:
Yi Kyeong CHUN
;
Jong Sun CHOI
;
Je G CHI
- Publication Type:Case Report
- Keywords:
Frontal lobe;
Malformations of cortical development;
Chorioamnionitis;
Neuronal migration disorders
- MeSH:
Autopsy;
Chorioamnionitis;
European Continental Ancestry Group;
Female;
Fetus;
Frontal Lobe;
Humans;
Intellectual Disability;
Language Development;
Male;
Malformations of Cortical Development;
Muscle Spasticity;
Neuronal Migration Disorders;
Neurons;
Pregnancy;
Quadriplegia
- From:Korean Journal of Pathology
2011;45(Suppl 1):S62-S65
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bilateral frontal polymicrogyria is a recently recognized syndrome characterized by symmetric polymicrogyria of both frontal lobes that presents with delayed motor and language development, spastic quadriparesis, and variable mental retardation. However, the postmortem findings of this syndrome are not fully elaborated. Here we describe an autopsy case of bilateral frontal polymicrogyria in a male fetus delivered at 22 weeks gestation due to extensive chorioamnionitis. The microscopic findings included a thinned cortical plate with fair neuronal maturation. There were no signs of neuronal damage and the white matter was unremarkable.
