Brucella Prostatitis: A First Case Report Diagnosed in Korea.
10.4132/KoreanJPathol.2011.45.S1.S66
- Author:
Seong Yeol RYU
;
Hyun Ah KIM
;
Jiyoung PARK
;
Misun CHOE
;
Kunyoung KWON
- Publication Type:Case Report
- Keywords:
Brucella;
Prostatitis;
Granuloma
- MeSH:
Biopsy, Needle;
Brucella;
Brucellosis;
Diagnosis, Differential;
Doxycycline;
Fever;
Granuloma;
Humans;
Inflammation;
Korea;
Low Back Pain;
Middle Aged;
Mycobacterium tuberculosis;
Necrosis;
Polymerase Chain Reaction;
Prostate;
Prostate-Specific Antigen;
Prostatitis;
Rifampin
- From:Korean Journal of Pathology
2011;45(Suppl 1):S66-S69
- CountryRepublic of Korea
- Language:English
-
Abstract:
Brucellosis is a zoonosis caused by several species of Brucella. Brucellosis is usually an acute or sub-acute febrile illness that histologically develops granulomatous inflammation. Brucella prostatitis is a very rare complication and is usually accompanied by epididymo-orchitis. We now report a case of histologically proven granulomatous prostatitis due to Brucella without clinical evidence of epididymo-orchitis. A 61-year-old farmer presented with myalgia, low back pain, and fever. A needle biopsy of the prostate was performed due to symptoms of urinary frequency and high prostate specific antigen levels (17.3 ng/mL). Histologically, the prostate showed granulomatous inflammation without caseous necrosis. Polymerase chain reaction (PCR) studies of blood and prostatic tissue for Brucella were positive, while a PCR study for Mycobacterium tuberculosis was negative. The patient was treated with doxycycline and rifampin. A possibility of Brucella prostatitis should be considered in the differential diagnosis of granulomatous prostatitis or prostatitis of unknown origin associated with or without epididymo-orchitis.