Two Cases of Hemolytic Uremic Syndromes Associated with Infectious Diarrhea in Adult.
- Author:
Byung Su KIM
1
;
Woo Seung SHIN
;
Jae Sun CHANG
;
Sung Rae KIM
;
Young Ok KIM
;
Sang Woo KIM
;
Yang Ree KIM
;
Moon Won KANG
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Human;
Adult;
Hemolytic uremic syndrome;
Infectious diarrhea
- MeSH:
Adult*;
Anemia, Hemolytic;
Child;
Communicable Diseases;
Diarrhea*;
Endothelial Cells;
Escherichia coli;
Fever;
Hemolytic-Uremic Syndrome;
Humans;
Organ Transplantation;
Pregnancy;
Renal Insufficiency;
Shiga Toxins;
Thrombocytopenia;
Thrombosis;
Transplants
- From:Korean Journal of Infectious Diseases
1997;29(2):165-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hemolytic uremic syndrome (HUS) is defined by the triad of renal failure, thrombocytopenia and hemolytic anemia. HUS is usually developed by infectious disease in children, but occasionally in adults. Infectious disease associated with HUS is characterized by fever and diarrhea-commonly related with Escherichia coli O157:H7. Verotoxin (Shiga-like toxin) produced by E. coli damage the endothelial cells, promote local thrombosis and finally step to HUS. Other causes of HUS include drugs, pregnancy, organ transplantation and malignant tumor. We report two adult patients cases of HUS associated with infectious diarrhea.
