Malignancy in Renal Transplant Recipients.
- Author:
Gun Hwan KIM
1
;
Jae Ho CHOI
;
Joon Heon JEONG
Author Information
1. Department of General Surgery, Maryknoll Hospital, Busan, Korea. mkhgs@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Malignancy;
Renal transplantation
- MeSH:
Adenocarcinoma;
Breast;
Breast Neoplasms;
Carcinoma, Lobular;
Carcinoma, Squamous Cell;
Cervix Uteri;
Diagnosis;
Drug Therapy;
Female;
Follow-Up Studies;
Graft Survival;
Humans;
Immunosuppressive Agents;
Incidence;
Kidney Transplantation;
Mass Screening;
Mortality;
Retrospective Studies;
Stomach;
Stomach Neoplasms;
Survival Rate;
Transplantation*
- From:The Journal of the Korean Society for Transplantation
2002;16(2):215-218
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Survival rate after renal transplantation has increased in according to the prolonged graft survival due to a development of new immunosuppressive agents and operative techniques. Therefore, the develpment of malignancy in renal transplant recipients has become the major cause of morbidity and mortality. METHODS: The retrospective analysis was performed in 4 patients with malignancy among the 315 patients who underwent kidney transplantation in our hospital from August 1990 to March 2001 and 1 patient with malignancy who underwent kidney transplantation in other hospital and was followed up in our hospital. RESULTS: In five malignancy, 3 were adenocarcinoma in stomach, 1 lobular carcinoma in breast and 1 squamous cell carcinoma in uterine cervix. The mean age of these patients at diagnosis of malignancy was 48.4 (35~60) and the average interval between renal transplantation and diagnosis of malignancy was 69.8 months. Surgical resection was done in all five patients. Chemotherapy was performed in 1 patients with advanced gastric cancer and 1 patient with breast cancer. Four patients are now alive and one patient was lost during follow-up period. CONCLUSION: We reviewed the incidences and types of malignancy after renal transplantation in our hospital. Regular screening and careful surveillance are highly recommended in patients after renal transplantation.
