Strategies to Prevent Transfusion-Transmitted Infection in Blood Centers.
10.17945/kjbt.2017.28.3.211
- Author:
Dong Woo SHIN
1
;
Hyungsuk KIM
;
Boram KIM
;
Tae Yeul KIM
;
Yun Ji HONG
;
Taek Soo KIM
;
Jeong Su PARK
;
Eun Young SONG
;
Kyoung Un PARK
;
Kyou Sup HAN
Author Information
1. Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea. aeiea@snu.ac.kr
- Publication Type:Review
- Keywords:
Transfusion-transmitted infection;
Donor screening;
Bacterial contamination
- MeSH:
Communicable Diseases;
Donor Selection;
Humans;
Mass Screening;
Medical History Taking;
Nucleic Acid Amplification Techniques;
Tissue Donors
- From:Korean Journal of Blood Transfusion
2017;28(3):211-224
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
There has been continuous effort to prevent transfusion-transmitted infection (TTI). Strategies to prevent TTI can be divided into two components: first, determining donor eligibility, and second, managing bacterial contamination of blood products. To determine donor eligibility, medical history taking and screening tests for infectious diseases should be performed. To prevent bacterial contamination, blood collection process should be aseptic, tests for bacterial detection should be performed, and an application of pathogen reduction technology should also be considered. In this review, screening test items and methods, including nucleic acid amplification tests for determining donor eligibility, and precautions for blood collection, bacterial detection methods, and pathogen reduction technology for the prevention of bacterial contamination of blood products were discussed in detail.
