Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells.
10.5395/JKACD.2010.35.6.473
- Author:
Choo Ryung CHUNG
1
;
Euiseong KIM
;
Su Jung SHIN
Author Information
1. Department of Orthodontics, Yonsei University College of Dentistry, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Bioaggregate;
Biocompatibility;
MTA;
Periodontal ligament cell;
Pulp cell
- MeSH:
Bicuspid;
Calcium Hydroxide;
Cell Culture Techniques;
Cell Survival;
Glutamates;
Guanine;
Humans;
Hydroxyapatites;
Periodontal Ligament;
Seeds;
Silicates;
Pemetrexed
- From:Journal of Korean Academy of Conservative Dentistry
2010;35(6):473-478
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: This study was performed to investigate the biocompatibility of newly introduced Bioaggregate on human pulp and PDL cells. MATERIALS AND METHODS: Cells were collected from human pulp and PDL tissue of extracted premolars. Cell culture plate was coated either with Bioaggregate or white MTA, then the same number of cells were poured to cell culture dishes. Cell attachment and growth was examined under a phase microscope after 1,3 and 7 days of seeding. Cell viability was measured and the data was analyzed using Student t-test and one way ANOVA. RESULTS: Both types of cells used in this study were well attached and grew healthy on Bioaggregate and MTA coated culture dishes. No cell inhibition zone was observed in Bioaggregate group. There was no statistical difference of viable cells between bioaggreagte and MTA groups. CONCLUSIONS: Bioaggregate appeared to be biocompatible compared with white MTA on human pulp and PDL cells.
