A case of idiopathic pulmonary hemosiderosis with seasonal recurrence.
10.3345/kjp.2009.52.2.256
- Author:
Ga Young KWAK
1
;
Na Young LEE
;
Moon Hee LEE
;
Soo Young LEE
;
Seung Yun CHUNG
;
Jin Han KANG
;
Dae Chul JEONG
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea. dcjeong@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Idiopathic pulmonary hemosiderosis;
Seasonal recurrence
- MeSH:
Anemia, Iron-Deficiency;
Child;
Hemoptysis;
Hemorrhage;
Hemosiderosis;
Humans;
Lung Diseases;
Macrophages;
Pulmonary Fibrosis;
Rare Diseases;
Recurrence;
Respiratory Insufficiency;
Seasons
- From:Korean Journal of Pediatrics
2009;52(2):256-260
- CountryRepublic of Korea
- Language:English
-
Abstract:
Idiopathic pulmonary hemosiderosis (IPH) is a rare disease affecting mostly children. This disorder is characterized by recurrent episodes of hemoptysis, bilateral diffuse pulmonary infiltrates, and iron-deficiency anemia. An acute fulminant alveolar hemorrhage can be fatal due to respiratory failure, while chronic hemorrhage leads to hemosiderin-laden macrophages and pulmonary fibrosis. Genetic, autoimmune, allergic, environmental, and metabolic mechanisms of pathogenesis have been suggested, but the etiology of IPH remains unknown. We report on a 9-year-old girl with idiopathic pulmonary hemosiderosis who showed seasonal recurrences without cause.
