Etiologies and prognostic factors of chronic cor pulmonale.
10.4046/trd.1999.47.5.609
- Author:
Yoong In PARK
1
;
Sang Hyun KIM
;
Jae Kyung HA
;
Seong Ho KIM
;
Byoung Jae AN
;
Woo Hyeong BAE
;
Hyeon Gook LEE
;
Kook Jin CHUN
;
Taek Jong HONG
;
Soon Kew PARK
;
Yung Woo SHIN
Author Information
1. Department of Internal Medicine, College of medicine, Pusan National University, Korea.
- Publication Type:Original Article
- MeSH:
Blood Gas Analysis;
Busan;
Diagnosis;
Echocardiography;
Female;
Heart Ventricles;
Humans;
Lung;
Male;
Multivariate Analysis;
Pulmonary Disease, Chronic Obstructive;
Pulmonary Heart Disease*;
Respiratory Function Tests;
Serum Albumin;
Survival Rate;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
1999;47(5):609-617
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The aims of this study were to assess the etiologies, survival and prognositic factors of patients with chronic cor pulmonale visited Pusan National University Hospital. METHODS: This study included 103 patients with chronic cor pulmonale. There were 67 men and 36 women. The diagnosis of chronic cor pulmonale was primarily based on the presence of underlying lung disorder and echocardiographic finding of enlarged or hypertrophied right ventricle. Other clinical data including patients' symptoms and signs, findings of arterial blood gas analysis, hematologic and biochemical laboratory and pulmonary function test were assessed. RESULTS: The most common underlying lung disorder was pulmonary tuberculosis (59.2%) and chronic obstructive pulmonary disease was the next (28.2%). The survival rate was 57% in one year, 45% in two years, and 34% in three years. The prognostic factors were maximal voluntary ventilation(MVV), forced vital capacity(FVC), FEV1, serum Na, vital capacity(VC), serum albumin and peak expiratory flow(PEF) in univariate analysis. And in multivariate analysis, serum albumin(p=0.0144) and VC(p=0.0078) were statistically significant. CONCLUSION: Pulmonary tuberculosis was the most important underlying lung disorder in chronic cor pulmonale. The survival rate was 57% in one year, 45% in two years, and 34% in three years. Serum albumin(p=0.0144) and VC(p=0.0078) were statistically significant prognostic factors.
