A Case of Disseminated Cutaneous Infection Caused by Fusarium oxysporum in an Immunocompromised Patient.
- Author:
Sook Hee LIM
1
;
Dong Won LEE
;
Jun Young LEE
;
Ji Hyang LIM
;
Kyung Ja HAN
;
Baik Kee CHO
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Immunocompromised;
F. oxysporum;
Opportunistic infection
- MeSH:
Anti-Bacterial Agents;
Child, Preschool;
Dermis;
Drug Therapy;
Fever;
Fungi;
Fusarium*;
Humans;
Hyphae;
Immunocompromised Host*;
Immunosuppressive Agents;
Male;
Necrosis;
Opportunistic Infections;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Purpura;
Skin
- From:Korean Journal of Medical Mycology
2000;5(1):24-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
With the wide and extensive use of immunosuppressive agents and broad-spectrum antibiotics, opportunistic fungla infections have been increased. Fusarium spp. are known to be significant emerging pathogens of opporthunistic local infection. But very rarely it may cause fatalc systemic infection. A 4-year-old boy with acute lymphocytic leukemia develped asymptomatic disseminated purpura with high fever unresponsive to the antibiotics during chemotherapy. The skin lesions gradually increased in size and number, and prgreassed to forming central necrosis. Many septated hyphae and variable sized spore-like fungal elements are found in the epidrmis, dermis and subcuit on histologic sections. The pathogenic fungus was idenified as Fusarium oxysporum by culture and scanning electronic microscopic findings.
