Autolysed antigen-extracted allogeneic bone for repair of diaphyseal bone defects in rabbits.
10.3349/ymj.1990.31.3.251
- Author:
Chang Dong HAN
1
;
Ho Jung KANG
;
Eung Shick KANG
;
Kyoo Ho SHIN
;
Nam Hyun KIM
Author Information
1. Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Autolysed antigen-extracted allogeneic bone (AAA bone);
bone defect
- MeSH:
Animal;
*Bone Transplantation/immunology;
Bone and Bones/immunology;
Graft Survival;
Rabbits;
Support, Non-U.S. Gov't;
Transplantation, Homologous/immunology
- From:Yonsei Medical Journal
1990;31(3):251-257
- CountryRepublic of Korea
- Language:English
-
Abstract:
Autolysed antigen-extracted allogeneic bone (AAA bone) was used to bridge a large osteoperiosteal gap in the diaphysis of the radius of 50 rabbits. Periodic observations of the graft were made clinically, radiologically and histologically every week up to fourteen weeks. The continuity of the radius was evaluated macroscopically and histologically. The AAA bones were progressively resorbed and replaced by the new bone. The bone remodelled to the mature tubular bone and did not undergo absorption during the experimental period. The AAA bone proceeded to be an osteoinductive and osteoconductive material. There were no appreciable histologic signs of immune or foreign body reaction.
