A case of Leigh's disease with initial manifestation of dystonia.
10.3349/ymj.1990.31.3.274
- Author:
Chae Woo CHUNG
1
;
Sung Hee HWANG
;
Young Chul CHOI
;
Young Ho SOHN
;
Jin Soo KIM
;
Byung Chul LEE
;
Je Geun CHI
Author Information
1. Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Leight's disease;
subacute necrotizing encephalomyelopathy;
dystonia;
pleoconial mitochondrial myopathy
- MeSH:
Basal Ganglia/pathology;
Case Report;
Dystonia/diagnosis/*etiology;
Energy Metabolism;
Human;
Infant;
Leigh Disease/*diagnosis/metabolism/pathology;
Male;
Muscles/pathology
- From:Yonsei Medical Journal
1990;31(3):274-279
- CountryRepublic of Korea
- Language:English
-
Abstract:
A case of Leigh's disease (subacute necrotizing encephalomyelopathy) is reported with such noteworthy features as early onset, dystonia, paraparesis the presence of low attenuation areas in both basal ganglias on computerized tomography of the brain and the presence of a high signal intensity in both basal ganglias in T2 weighted image by MR. The electron microscopic findings of muscle biopsy are suggestive of pleoconial mitochondrial myopathy.
