Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder.
10.3346/jkms.2010.25.5.781
- Author:
Min Joo KIM
1
;
Inho KIM
;
Hyun Mi BAE
;
Kyungsuk SEO
;
Namjun PARK
;
Sung Soo YOON
;
Seonyang PARK
;
Byoung Kook KIM
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. kim_dajung@hanmail.net
- Publication Type:Case Reports
- Keywords:
Posttransplant Lymphoproliferative Disorder, Hematopoietic Stem Cell Transplantation;
Liver Transplantation
- MeSH:
Adolescent;
Female;
Hematopoietic Stem Cell Transplantation/*methods;
Humans;
Liver Transplantation/*adverse effects;
Lymphoproliferative Disorders/*etiology/*surgery;
Treatment Outcome
- From:Journal of Korean Medical Science
2010;25(5):781-784
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed posttransplant lymphoproliferative disorder (PTLD). Immunosuppression reduction was attempted, but it produced no therapeutic effect. Fourteen months after liver transplantation, she received a second HSCT due to engraftment failure, and PTLD resolved completely. The second HSCT can serve as cellular therapy for PTLD.
