Contrast-induced Nephropathy in Patients Undergoing Percutaneous Coronary Angiography and its Clinical Characteristics.
- Author:
Won CHOI
1
;
Hyun Min LIM
;
Hye Jin WON
;
Hye Kyeong PARK
;
Ban Suck LEE
;
Hyo Seung AHN
;
Hye Won JOO
;
Sang Hyun KIM
;
Won Do PARK
Author Information
1. Department of Internal Medicine, Il-gok Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Contrast media;
Coronary angiography;
Renal insufficiency;
Uric acid
- MeSH:
Anemia;
Contrast Media;
Coronary Angiography;
Creatinine;
Heart Failure;
Humans;
Hyperuricemia;
Incidence;
Medical Records;
Renal Insufficiency;
Retrospective Studies;
Risk Factors;
Uric Acid
- From:Korean Journal of Nephrology
2008;27(1):55-61
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Contrast media-induced nephropathy (CIN) following coronary angiography is associated with an increased mortality and morbidity. We investigated the incidence of nephrotoxicity, clinical characteristics, laboratory characteristics and risk factors of CIN in patients undergoing coronary angiography. METHODS: We retrospectively evaluated the medical records of 555 patients who had undergone coronary angiography at the Sanggye Paik Hospital, from January 2004 to December 2005. We defined CIN as any increase in the creatinine value of more than 0.5 mg/dL or 50% of baseline value. RESULTS: Among 555 patients, CIN developed in 10 of 48 patients (20.8%) with renal insufficiency (serum creatinine > or =1.4 mg/dL) and in 7 of 507 patients (1.4%) without renal insufficiency (p<0.001). Decreased renal function, congestive heart failure, higher baseline uric acid, lower baseline albumin and age > or =65 years were the significant predictors of CIN. There were no statistical differences in contrast type and volume according to the development of CIN. CONCLUSION: Our data supported the assumption that renal insufficiency, congestive heart failure, hyperuricemia and anemia may be the risk factors of developing CIN.
