A Case of Focal Segmental Glomerulosclerosis Associated with Renal Cell Carcinoma.
- Author:
Hun JEONG
1
;
Stephen YongGu LEE
;
Hyo Young KIM
;
Sang Hoon KIM
;
Myung Su SON
;
Yang Hyun CHO
;
Hyung Jong KIM
;
Dong Ho YANG
;
Yong Hee LEE
;
Sun Won HONG
Author Information
1. Department of Internal Mecidine, College of Medicine, Pochon CHA University, Sungnam, Korea. khj04@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Focal segmental glomerulosclerosis;
Renal cell carcinoma;
Nephrotic syndrome
- MeSH:
Biopsy;
Carcinoma, Renal Cell;
Glomerulonephritis, Membranous;
Glomerulosclerosis, Focal Segmental;
Hematologic Neoplasms;
Humans;
Kidney;
Nephrosis, Lipoid;
Nephrotic Syndrome;
Proteinuria;
Renal Insufficiency
- From:Korean Journal of Nephrology
2008;27(1):127-132
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The association between malignancy and glomerular disease has been reported in older patients. Although the relationship between membranous glomerulonephritis or minimal change disease and solid tumors or hematologic malignancies, respectively, are known widely, focal segmental glomerulosclerosis have been described rarely in patients with solid tumors. We describe a patient with renal cell carcinoma who presented to nephrotic syndrome, volume overload and renal failure. On renal biopsy at contra-lateral kidney of renal cell carcinoma, the patient was diagnosed at focal segmental glomerulosclerosis. The proteinuria and renal function were ameliorated after resection renal cell carcinoma. We suggest that the focal segmental glomerulosclerosis is associated with renal cell carcinoma. This is the first case of the clinical cause of focal segmental glomerulosclerosis associated with renal cell carcinoma of papillary type.
