A Case of Primary Amyloidosis with Nephrotic Syndrome and Factor X Deficiency.
- Author:
Min Young KIM
1
;
Soo Yeong KWAK
;
Kyung Hee KIM
;
Ji In LEE
;
Young Eun HA
;
Dae Joong KIM
;
Ha Young OH
;
Jung Eun LEE
;
Woo Seong HUH
;
Yoon Goo KIM
Author Information
1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ygkim26@skku.edu
- Publication Type:Case Report
- Keywords:
Factor X deficiency;
Nephrotic syndrome;
Amyloidosis
- MeSH:
Amyloidosis;
Biopsy;
Bone Marrow;
Electrophoresis;
Factor X;
Factor X Deficiency;
Hemorrhage;
Humans;
Middle Aged;
Nephrotic Syndrome;
Prothrombin Time
- From:Korean Journal of Nephrology
2008;27(1):133-136
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of nephrotic syndrome and factor X deficiency secondary to primary amyloidosis. A 58-year-old man was referred to our hospital for evaluation of nephrotic syndrome and bleeding tendency. He was confirmed to have primary amyloidosis by renal biopsy, immunofixation electrophoresis and bone marrow findings. His bleeding tendency was due to prothrombin time prolongation caused by isolated factor X deficiency. If any patient with nephrotic syndrome has bleeding tendency due to coagulation abnormalities, that patient should be considered to have factor X deficiency secondary to primary amyloidosis.
