Managing alcoholic liver disease.
10.3350/cmh.2015.21.3.212
- Author:
Vijay H SHAH
1
Author Information
1. Gastroenterology Research Unit, Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. shah.vijay@mayo.edu
- Publication Type:Review
- Keywords:
Liver transplantation;
Alcoholic hepatitis;
Corticosteroids;
Alcohol
- MeSH:
Adrenal Cortex Hormones/therapeutic use;
Biomarkers/analysis;
Humans;
Interleukins/metabolism;
Liver Diseases, Alcoholic/diagnosis/*therapy;
Liver Transplantation;
Pentoxifylline/therapeutic use;
Prognosis
- From:Clinical and Molecular Hepatology
2015;21(3):212-219
- CountryRepublic of Korea
- Language:English
-
Abstract:
Alcoholic liver disease continues to be a significant cause of liver-related morbidity and mortality throughout the world. A number of diagnostic and prognostic models have been developed in the management of this condition, although specific roles for liver biopsy still remain particularly in the setting of alcoholic hepatitis. Despite a large number of recent treatment trials, the ideal pharmacotherapy approach remains undefined. Most essential is the supportive care and focus on abstinence and nutrition. Owing in part to a great deal of attention from governmental funding sources, a number of new treatment approaches are undergoing rigorous evaluation, hopefully providing future treatment options in this very severe condition.
