A Case of Transient Central Diabetes Insipidus after Aorto-Coronary Bypass Operation.
10.3346/jkms.2012.27.9.1109
- Author:
Chung Hoon YU
1
;
Jang Hee CHO
;
Hee Yeon JUNG
;
Jeong Hoon LIM
;
Mi Kyung JIN
;
Owen KWON
;
Kyung Deuk HONG
;
Ji Young CHOI
;
Se Hee YOON
;
Chan Duck KIM
;
Yong Lim KIM
;
Gun Jik KIM
;
Sun Hee PARK
Author Information
1. Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea. sh-park@knu.ac.kr
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Polyuria;
Central Diabetes Insipidus;
Aorto-Coronary Bypass
- MeSH:
Adult;
Antidiuretic Agents/therapeutic use;
Coronary Artery Bypass/*adverse effects;
Coronary Vessels;
Deamino Arginine Vasopressin/therapeutic use;
Diabetes Insipidus, Neurogenic/*diagnosis/drug therapy/etiology;
Humans;
Hypothalamus/radionuclide imaging;
Magnetic Resonance Imaging;
Male;
Pituitary Gland/radionuclide imaging;
Polyuria/diagnosis/etiology;
Postoperative Complications/*diagnosis/drug therapy/etiology
- From:Journal of Korean Medical Science
2012;27(9):1109-1113
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG). A 44-yr-old male underwent a CABG operation. An hour after the operation, the patient developed polyuria and was diagnosed with central DI. The patient responded to desmopressin and completely recovered five days after surgery. It is probable that transient cerebral ischemia resulted in the dysfunction of osmotic receptors in the hypothalamus or hypothalamus-pituitary axis during CPB. It is also possible that cardiac standstill altered the left atrial non-osmotic receptor function and suppressed ADH release. Therefore, we suggest that central DI is a possible cause of polyuria after CPB.
