Primary Sjogren's syndrome presenting as acute transverse myelitis.
- Author:
Hyo Jin CHOI
1
;
Kichul SHIN
;
Eun Ha KANG
;
Churl Hyun IM
;
Yun Jong LEE
;
Eun Bong LEE
;
Yeong Wook SONG
Author Information
1. Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. ysong@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Sjogren's syndrome;
Transverse myelitis;
Corticosteroid;
Cyclophosphamide
- MeSH:
Adult;
Autoimmune Diseases;
Cyclophosphamide;
Exocrine Glands;
Female;
Humans;
Leg;
Magnetic Resonance Imaging;
Methylprednisolone;
Myelitis, Transverse*;
Prednisolone;
Sjogren's Syndrome*
- From:Korean Journal of Medicine
2005;68(4):463-466
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sjogren's syndrome is one of chronic inflammatory autoimmune diseases involving exocrine gland. Involvement of central nerve system was rarely reported. We report a case of primary Sjogren's syndrome presenting as transverse myelitis in 37-year-old female who complained of tingling sense in both legs and voiding difficulty. Magnetic resonance imaging shows high signal intensity with cord swelling from C6 to T7 in T2 weighted image. The patient received intravenous methylprednisolone (1,000 mg/day) for 10 days followed by prednisolone and intravenous monthly cyclophosphamide with subsequent clinical improvement.
