A Case of Acute Generalized Exanthematous Pustulosis.
- Author:
Sang Ju LEE
;
Sung Nam CHANG
;
Wook Hwa PARK
- Publication Type:Case Report
- Keywords:
Acute generalized exanthematous pustulosis;
Diltiazem
- MeSH:
Acute Generalized Exanthematous Pustulosis*;
Aged;
Biopsy;
Blood Sedimentation;
Diltiazem;
Erythema;
Erythema Multiforme;
Extremities;
Female;
Fever;
Humans;
Hypertension;
Leukocytosis;
Neutrophils;
Psoriasis;
Skin
- From:Korean Journal of Dermatology
1998;36(1):125-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute generalized exanthematous pustulosis(AGEP) is a disease entity caused mostly by drugs or viral infections. Clinically it manifests as generalized erythema, erythema multiforme and amicrobial pustules with fever. Histologically, AGEP is composed of neutrophilic subcorneal and spongiform pustules. A 70-year-old female, with no personal or family history of psoriasis, was given medication including diltiazem for hypertension. Fourteen days after taking the medications, pustular eruptions appeared on the face and rapidly spread to the trunk and limbs. A Laboratory examination revealed neutrophilic leukocytosis and an elevated erythrocyte sedimentation rate. The skin biopsy showed subcorneal and spongiform pustules. We report here a case of AGEP probably due to diltiazem.