Factors Associated With Upper Extremity Motor Recovery After Repetitive Transcranial Magnetic Stimulation in Stroke Patients.
10.5535/arm.2015.39.2.268
- Author:
Jong Hwa LEE
1
;
Sang Beom KIM
;
Kyeong Woo LEE
;
Min Ah KIM
;
Sook Joung LEE
;
Su Jin CHOI
Author Information
1. Department of Physical Medicine & Rehabilitation, Dong-A University College of Medicine, Busan, Korea. mail1002zoo@hanmail.net
- Publication Type:Original Article
- Keywords:
Stroke;
Transcranial magnetic stimulation;
Motor function
- MeSH:
Aphasia;
Arm;
Classification;
Hand;
Humans;
Motor Cortex;
Paresis;
Stroke*;
Transcranial Magnetic Stimulation*;
Upper Extremity*
- From:Annals of Rehabilitation Medicine
2015;39(2):268-276
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To determine factors associated with motor recovery of the upper extremity after repetitive transcranial magnetic stimulation (rTMS) treatment in stroke patients. METHODS: Twenty-nine patients with subacute stroke participated in this study. rTMS was applied to the hand motor cortex for 10 minutes at a 110% resting motor threshold and 10 Hz frequency for two weeks. We evaluated the biographical, neurological, clinical, and functional variables, in addition to the motor-evoked potential (MEP) response. The Manual Function Test (MFT) was performed before, immediately after, and two weeks after, the treatment. Patients were divided into a responder and non-responder group according to their respective improvements on the MFT. Data were compared between the two groups. RESULTS: Patients with exclusively subcortical stroke, absence of aphasia, the presence of a MEP response, high scores on the Mini-Mental Status Examination, Motricity Index arm score, Functional Independence Measure, and Functional Ambulatory Classification; and a shorter period from stroke onset to rTMS were found to be significantly associated with a response to rTMS. CONCLUSION: The results of this study suggest that rTMS may have a greater effect on upper extremity motor recovery in stroke patients who have a MEP response, suffer an exclusively subcortical stroke, mild paresis, and have good functional status. Applying rTMS early would have additional positive effects in the patients with the identified characteristics.
