Antifungal Effects of the Extracts and Essential Oils from Foeniculum vulgare and Illicium verum against Candida albicans.
- Author:
Sung Ho PARK
1
;
Inwha SEONG
Author Information
1. Department of Microbiology, College of Medicine, Korea University, Korea. inwha@korea.ac.kr
- Publication Type:Original Article
- Keywords:
Illicium verum;
Extract;
Antifungal activity;
Candida albicans
- MeSH:
Benzene;
Candida;
Candida albicans;
Candidiasis;
Female;
Foeniculum;
Gastrointestinal Tract;
Humans;
Illicium;
Methylene Chloride;
Mucous Membrane;
Oils, Volatile;
Plants, Medicinal;
Recurrence;
Skin
- From:Korean Journal of Medical Mycology
2010;15(4):157-164
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Candida albicans is a member of the normal flora of the skin, mucous membrane and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women in childbearing age, Majority of the cases are caused by C. albicans and recurrence is common in spite of topical treatment. OBJECTIVE: The purpose of this study is to develop the antifungal agent from the medicinal herbs traditionally used in Korea. METHOD: In this study, the extracts and essential oils from Foeniculum vulgare and Illicium verum were examined for antifungal activities against C. albicans. RESULT: Dichloromethane extracts and essential oils from Foeniculum vulgare and Illicium verum showed antifungal activity against C. albicans. One fraction from Illicium verum with antifungal activity was founf out as 1-methoxy-4-(2-prophenyl) benzene. CONCLUSION: Dichloromethane extract and 1-methoxy-4-(2-prophenyl) benzene with antifungal activity from Illicium verum could be the candidate for a new antifungal agent for candidiasis and other fungal diseases.
