Development of Liver Cirrhosis in a Elderly Healthy Hepatitis B Carrier with Rheumatoid Arthritis Treated with Low-dose Methotrexate (MTX).
- Author:
Mi Hee KONG
1
;
Tae Young LEE
;
A Ryn KIM
;
Nam Seok JOO
;
Kwang Min KIM
Author Information
1. Department of Family Medicine and Community Health, Ajou University College of Medicine, Suwon, Korea. mdoc@nate.com
- Publication Type:Case Report
- Keywords:
MTX;
HBV healthy carrier;
elderly;
rheumatoid arthritis;
liver cirrhosis
- MeSH:
Aged*;
Arthritis, Rheumatoid*;
Female;
Fibrosis;
Hepatitis B*;
Humans;
Liver Cirrhosis*;
Methotrexate*
- From:Journal of the Korean Academy of Family Medicine
2006;27(12):1013-1017
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Methotrexate (MTX) is the most widely used slow-acting anti-rheumatic agent in the treatment of rheumatoid arthritis. But, long-term administration of MTX can be complicated with liver fibrosis and even cirrhosis. We report the case in elderly woman with healthy Hepatitis B viral carrier patient who developed liver cirrhosis without viral replication after low-dose MTX therapy for rheumatoid arthritis.
