The results after more than 1 year of the histopathology of the gastric mucosa before and after eradication of H. pylori in patient with the gastro-duodenal perforation and ulceration
- Author:
Trung Thien Tran
- Publication Type:Journal Article
- Keywords:
Gastroduodenal ulcer
- MeSH:
Helicobacter pylori;
Peptic Ulcer
- From:Journal of Practical Medicine
2002;435(11):8-10
- CountryViet Nam
- Language:Vietnamese
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Abstract:
The Aims of this study were to investigate to the role of Helicobacter pylori (H. pylori) eradication in cases of perforated peptic ulcer treated by simple surgical closure. In a large prospective study, these patients with H. pylori positive were evaluated before and after H. pylori eradication (>2 months and >1 year). Changes of gastric mocosal histopathology were assessed. Results: Improvement or resolution on the outcome of gastritis and atrophy (P<0.001) demonstrated the efficacy of eradication therapy but intestinal metaplasia did not change. Conclusions: After successful eradication of H. pylori, these lesions were restored significantly, but intestinal metaplasia is questionable
