Comparison of Visceral Fat and Liver Fat as Risk Factors of Metabolic Syndrome.
10.3346/jkms.2012.27.2.184
- Author:
Jeongseob LEE
1
;
Dae Sung CHUNG
;
Jee Hyun KANG
;
Byung Yeon YU
Author Information
1. Department of Family Medicine, Konyang University Hospital, Daejeon, Korea. jeehyunkang@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Metabolic Syndrome;
Visceral Fat;
Liver Fat
- MeSH:
Adolescent;
Adult;
Aged;
Blood Pressure;
Body Composition;
Demography;
Fatty Liver/*complications;
Female;
Humans;
Intra-Abdominal Fat/*anatomy & histology/radiography;
Liver/anatomy & histology/radiography;
Logistic Models;
Male;
Metabolic Syndrome X/diagnosis/epidemiology/*etiology;
Middle Aged;
Odds Ratio;
Risk Factors;
Sex Factors;
Spleen/anatomy & histology/radiography;
Tomography, X-Ray Computed;
Young Adult
- From:Journal of Korean Medical Science
2012;27(2):184-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
The principal objective of this study was to determine whether visceral fat or liver fat is a more relevant risk factor for metabolic syndrome. A total of 98 subjects aged 18-65 yr, who visited a health promotion center in a university hospital, were enrolled in this study. Metabolic syndrome was diagnosed based on the modified National Cholesterol Education Program's Adult Treatment Panel III report (NCEP-ATPIII) criteria. We defined the visceral obesity as a visceral fat area of > or = 100 cm2 which was acquired by CT at the L4-5 level. To evaluate fatty liver, we applied a liver-to-spleen attenuation ratio < or = 1.1 as measured by CT at the T12 level. We employed binary logistic regression models that used the presence or absence of metabolic syndrome as a dependent variable and age, sex, and the presence or absence of visceral obesity and fatty liver as independent variables. Visceral obesity was not found to be an independent variable as a risk factor of metabolic syndrome (odds ratio 2.7; 95% confidence interval 0.55-13.30), but fatty liver was found to be significant in this model (odds ratio 71.3; 95% CI 13.04-389.53). Our study suggests that liver fat may be a more important risk factor than visceral fat in terms of its association with metabolic syndrome.
