Monitoring and Safety of Azathioprine Therapy in Inflammatory Bowel Disease.
10.5223/pghn.2013.16.2.65
- Author:
Mi Jin KIM
1
;
Yon Ho CHOE
Author Information
1. Department of Pediatrics, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
- Publication Type:Review
- Keywords:
Azathioprine;
Inflammatory bowel diseases
- MeSH:
Azathioprine;
Inflammatory Bowel Diseases
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2013;16(2):65-70
- CountryRepublic of Korea
- Language:English
-
Abstract:
Azathioprine is the most common drug used to maintain clinical remission in inflammatory bowel disease. This drug is also important as a steroid-sparing agent in steroid-dependent and chronically active inflammatory bowel disease. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine. The dose of azathioprine has to be reduced or the therapy has to be discontinued frequently because of drug-induced toxicity. In this review, we discuss monitoring of thiopurines, adverse events, malignant complications and how to use azathioprine safely and usefully.
