Myofibrosarcoma of the Breast: A case report .
- Author:
Chan Kwon JUNG
;
Kyo Young LEE
;
Chang Suk KANG
;
Sang In SHIM
;
Byung Kee KIM
- Publication Type:Case Report
- Keywords:
Myofibrosarcoma;
Breast
- MeSH:
Actins;
Adipose Tissue;
Aged, 80 and over;
Breast*;
Collagen;
Fibronectins;
Humans;
Hyalin;
Muscle, Smooth;
Myofibroblasts;
Vimentin
- From:Korean Journal of Pathology
2000;34(1):96-98
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Myofibrosarcoma of the breast is a rare malignant mesenchymal tumor that has been reported in only four well documented cases so far. We report a case of myofibrosarcoma of the breast in an 88-year-old man who complained of a palpable mass for 1 year. Microscopically, the tumor consisted mainly of spindled cells, arranged in irregular fascicles and embedded in broad bands of dense hyalinized collagen. It showed ill-defined border infiltrating the adjacent adipose tissue, moderate cellular pleomorphism, and high mitotic rate (8~9/10 HPF). Immunohistochemical study confirmed myofibroblastic differentiation of the tumor cells with diffuse strong reaction for vimentin, smooth muscle actin, and fibronectin.
