A Case of Mesenteric Thrombosis and Partal Hypertension Associated with Antiphospholipid in a Patient with Hepatitis C.
- Author:
Ji Hyun LEE
1
;
Sang Mu JUNG
;
Jae Hong CHOI
;
Sang Woo OH
;
Byoung Gye NA
;
Seon Mee PARK
;
Sae Jin YUN
;
Kil Seun PARK
Author Information
1. Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea.
- Publication Type:Case Report
- Keywords:
Antiphospholipid antibodies;
Mesenteric thrombosis;
Portal hypertension;
Hepatitis C
- MeSH:
Abdominal Pain;
Adult;
Angiography;
Anti-Bacterial Agents;
Antibodies, Antiphospholipid;
Colon;
Connective Tissue Diseases;
Esophageal and Gastric Varices;
Estrogens, Conjugated (USP);
Hemorrhage;
Hepacivirus;
Hepatitis C Antibodies;
Hepatitis C*;
Hepatitis*;
Humans;
Hypertension*;
Hypertension, Portal;
Infarction;
Pancreatitis;
Shock, Septic;
Thrombocytopenia;
Thrombosis*;
Tomography, X-Ray Computed;
Ulcer;
Venous Thrombosis
- From:Korean Journal of Gastrointestinal Endoscopy
1997;17(6):841-846
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The gastrointestinal rnanifestations associated with antiphospholipid antibodies include Budd-Chiari syndroame, hepatic infarction, portal hypertension, pancreatitis, intestinal infarction, perforation, bleeding and ulceration. A 40-year old man, without prior thrombotic event, presented with severe abdominal pain for 3 days and septic shock. Multiple mesenteric venous thrombosis and colonic congestion were suggested by abdominal CT and angiography. Gastroendoscopy revealed esophageal varix and congestive gastropathy. Laboratory tests disclosed postive antiphospholipid antibodies, anti-HCV antibodies, HCV-PCR, prolonged PT, aPTT, thrombocytopenia and had no evidences of SLE and other connective tissue diseases. He was diagnosed as mutiple mesenteric thrombosis and portal hypertension associated with antiphospholipid antibodies in hepatitis C virus infection. He was improved with the antibiotics and intravenous vasopressors. He have had no other thrombotic events until one year after discharge.